Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Effect of transferring frozen-thawed embryos resulting from fertilization of immature oocytes matured one day in culture prior to intracytoplasmic sperm injection (ICSI) on implantation rates
Purpose: To evaluate whether it is efficacious to allow immature (metaphase I or germinal vesicle stage) oocytes to incubate one more day and then perform ICSI. Method: A retrospective study of frozen embryo transfers (ET) of deselected frozen embryos was performed to see if inclusion of a higher percentage of embryos derived from in vitro maturation of oocytes resulted in lower implantation rates. Results: The implantation rate following transfer of frozen-thawed embryos, where embryos derived from immature oocytes constituted ≤40% of the embryos (group I) was similar to group 2 with >40% (11.3% vs 9.8%). However, group 1 had a 10.2% implantation rate for viable (past first trimester) sacs vs only 4.3% for group 2. Conclusions: Pregnancies from transfer of frozen-thawed embryos derived from in vitro cultured immature oocytes are as likely to implant as the other deselected frozen-thawed embryos.