IMR Press / CEOG / Volume 29 / Issue 4 / pii/2002076

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Case Report

Successful treatment with carbimazole of a hyperthyroid pregnancy with hepatic impairment after propylthiouracil administration: a case report

Show Less
1 Second Endocrine Department, “Alexandra” General Hospital, Athens (Greece)
2 University Endocrine Unit, “Evgenidion” Hospital, Athens (Greece)
3 Department of Medicine, "Alexandra" General Hospital, Athens (Greece)
Clin. Exp. Obstet. Gynecol. 2002, 29(4), 302–305;
Published: 10 December 2002
Abstract

We report the case of a 27-year-old woman with hyperthyroidism during pregnancy. Antithyroid treatment with propylthiuouracil (PTU) resulted in elevated hepatic enzymes and after the 12th week of pregnancy tratment was changed to carbimazole (CBZ) The remaining pregnancy, delivery and follow-up period were uneventful for the mother and her offspring. Antithyroid treatment during pregnancy should allow the use not only of PTU but also of CBZ and methimazole.

Keywords
Thyrotoxicosis
Pregnancy
Propylthiouracil
Hepatotoxicity
Carbimazole
Share
Back to top