IMR Press / CEOG / Volume 28 / Issue 2 / pii/2001025

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Original Research

Successful treatment of cervical and simultaneous cervico-isthmic pregnancy with methotrexate

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1 Department of Obstetrics and Gynecology, University of Bari (Italy)
Clin. Exp. Obstet. Gynecol. 2001, 28(2), 89–90;
Published: 10 June 2001
Abstract

Objective: To describe the monitoring of a case of cervical and simultaneous cervico-isthmic pregnancy. Setting: University of Bari (Italy), Department of Obstetrics and Gynecology. Patient: A 30-year-old white woman, nulliparous, at 8 weeks of amenorrhoea. Intervention: Methotrexate and folinic acid administered systemically. Main Outcome Measure: Treatment success was defined as elimination of the cervical and cervico-isthmic preg­nancy, with non-invasive treatment and preservation of the uterus and normal ovarian activity restored. Result: Methotrexate and folinic acid were administered, elimination of a twin pregnancy with declining serum beta-hCG levels and with ultrasound was observed. The patient had only occasional dark vaginal bleeding and temporary movement of the transaminase. Conclusion: This case report shows that methotrexate is a valid, conservative and non-invasive treatment for a patient affected by cervical pregnancy who wishes to keep fertility.

Keywords
Ectopic pregnancy
Cervical pregnancy
Methotrexate
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