IMR Press / CEOG / Volume 27 / Issue 1 / pii/2000011

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Original Research

Sonographic parameters and hormonal status in lean and obese women with polycystic ovary syndrome

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1 Department of Obstetrics and Gynecology of "Alexandra" General Hospital, Athens (Greece)
Clin. Exp. Obstet. Gynecol. 2000, 27(1), 35–38;
Published: 10 March 2000
Abstract

A total of 34 patients with the diagnosis of polycystic ovary syndrome (PCOS) were recruited for this study. Weight distribution in lean PCOS women (n = 17) was 93.5% to 110.5% of nomal weight for height and age. In obese women (n = 17) this distribution was 119.5 to 146.5%. Serum testosterone (T), dehydroepiandrosterone sulfate (DHEA-S), D4-androstendione (D4-A), sex hormone binding globulin, (SHBG), 17-hydroxyprogesterone (17-OH PRG), I7b oestradiol (17b-E2), cortisol (CORT), follicle stimulating hormone (FSH), luteinizing hormone (LH), prolactin (PRL) and insulin (INS) were measured. Serum SHBG levels were lower in obese PCOS women (72.9 ± 16.2 nmol/L) than in lean PCOS women (99.6 ± 10.5) (p < 0.001). Fasting insulin levels were higher in obese PCOS women (30.4 ± 4.5 mUI/mL) than in lean PCOS women (14.2 ± 7.6 mUI/mL) (p < 0.001). Mean ovarian volume did not differ significantly between lean and obese PCOS women (12 5 ± 37 ml vs 16.l ± 5.3, p > 0.5). Endometnal thickness was roughly similar between the two groups. Endometrial surface area in lean PCOS women (7.6 ± 2.2 cm2) was lower than in obese PCOS women (10.1 ± 1.9 cm2) and the difference was significant (p < 0.01). 

Keywords
PCO
Hormonal status
Sonography findings
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