IMR Press / CEOG / Volume 26 / Issue 3-4 / pii/1999047

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 46 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Open Access Original Research

D-dimer after delivery in uncomplicated pregnancies

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1 Division of Obstetrics and Gynecology Laboratory Unit, City Hospital, Guastalla - RE (Italy)
Clin. Exp. Obstet. Gynecol. 1999, 26(3-4), 211–212;
Published: 10 September 1999

D-dimer is now widely used as a coagulation marker. During pregnancy the D-dimer level increases until term even in uncom­plicated pregnancies. The aim of the study was to establish the D-dimer immediately after delivery in uncomplicated pregnancies A rapid immunoturbidimetric assay for D-dimer determination was employed in 100 consecutive deliveries. D-dimer level increa­sed significantly in all women after delivery (increase from I to more than 10 times over the normal range). Conclusion: an increase in fibrinolysis is associated with pregnancy and delivery, and D-dimer level must be interpreted only in association with other cli­nical, laboratory and instrumental methods when pathological conditions (e.g. pulmonary embolism, deep vein thrombosis or dis­seminated coagulation) are suspected.

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