IMR Press / CEOG / Volume 26 / Issue 3-4 / pii/1999033

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 46 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Open Access Original Research

In vitro decidualization activity assay of human endometrial stromal cells

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1 Department of Obstetrics & Gynecology, Osaka City University Medical School, Osaka (Japan)
Clin. Exp. Obstet. Gynecol. 1999, 26(3-4), 166–170;
Published: 10 September 1999

To address the need for a simple and reliable system for evaluating the effects of bioactive substances on decidualization of endometrial stromal cells, we designed and tested an assay for measuring decidualization activity. With our assay, it is easy to examine the effects of various bioactive substances on endometrial stromal decidualization. For example, as shown in this study, it is now clear that neither RANTES nor gonadotropin releasing hormone agonist has any effect on endometrial stromal decidualization. Our simple assay has also made it possible to evaluate individual stromal decidualization activities and the regulation of decidualization.

Endometrial stromal cells
GnRH agonist
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