IMR Press / CEOG / Volume 26 / Issue 3-4 / pii/1999028

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 46 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Open Access Case Report

Trisomy 21 fetus co-existent with a partial molar pregnancy: case report

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1 Division of Gynecologic Oncology, Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology (USA)
2 Department of Pathology St. Vincent Hospitals and Health Services, Indianapolis, Indiana (USA)
Clin. Exp. Obstet. Gynecol. 1999, 26(3-4), 149–150;
Published: 10 September 1999

Background: Approximately l in l,000 pregnancies in the United States are complicated by the presence of a hydat心form mole A Medline search revealed no reported cases of a trisomic fetus co-existent from 1966-1998. We present the case of a patient, initially found to have hypertension, edema, and proteinuria in the first trimester, and later found to have a partial molar gestation co­existent with a trisomy 21 infant. Case Report: A 31-year-old female presented to her family practitioner in the first trimester and was found to have hypertension and proteinuria. A thorough work-up by a nephrologist revealed no cause. The patient was transferred to the Maternal-Fetal Medicine Service at 26 weeks’ and 1 day estimated gestational age. An amniocentesis revealed the presence of a fetus with trisomy 21 At 27 weeks’ and 3 days estimated gestational age, the patient underwent a cesarean delivery for a non-reassuring fetal heart rate Pathologic examination of the placenta revealed the presence of a partial hydatidiform molar pregnancy. Conclution: The present account represents the first reported case of a fetus with trisomy 21 co-existent with a partial hydati­diform mole.

Trisomy 21
Partial hydatidiform mole
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