IMR Press / CEOG / Volume 25 / Issue 3 / pii/1998036

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Original Research

The effect of 61 days of combined iron (Chemiron®) and single iron therapy on haemoglobin, packed cell volume, platelets and reticulocytes during pregnancy. Preliminary report

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1 Senior Lecturer/Consultant, Department of Obstetrics & Gynaecology, College of Medicine, University of Lagos, Idi-Araba, Senior Lecturer, School of Pharmacy, College of Medicine, University of Lagos, Idi-Araba (Lagos)
Clin. Exp. Obstet. Gynecol. 1998, 25(3), 107–111;
Published: 10 September 1998
Abstract

A 61-day short-term prospective study comparing the efficacy of Chemiron® capsules (Ferrous Fumarate 300 mg, Folic Acid 5 mg, Vitamin B 12 10 ug, Vitamin C 25 mg, Magnesium sulphate, 0.3mg and Zinc Sulphate 0.3mg) with conventional ferrous glu­conate and folic acid administration has shown that both haematinic regimens improve haematological indices in normal pregnant women. A significant rise in haemoglobin was seen in the Chemiron group on days 5 and 19 whereas a significant increase in packed cell volume was observed on days 5, 19 and 61. There were no significant differences between the mean value of platelets during the therapy period in either group. A significant rise in the mean reticulocyte values could be demonstrated in the Chemiron group throughout the study period. This study further shows that Chemiron has a better haematological effect than Ferrous Gluconate at the dosage used.

Keywords
Combined Iron (Chemiron®)
Single iron therapy
Effect on pregnancy
Haemoglobin
Packed cell volume
Platelets and reticulocyte level
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