IMR Press / CEOG / Volume 24 / Issue 3 / pii/1997056

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Original Research

Which is the threshold glycose value for further investigation in pregnancy?

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1 2nd Department of Obstetrics and Gynecology, University of Athens, Areteion Hospital, Athens - Greece
Clin. Exp. Obstet. Gynecol. 1997, 24(3), 171–173;
Published: 10 September 1997
Abstract

The aim of this study was to investigate the lower threshold glycose value in a 50 gr-1 hour screening test for further testing m diagnosing gestational diabetes mellitus (GDM). Our study consisted of 602 pregnant women between 24-28 weeks of gestation, who received a 50 gr glycose load followed by glycose determination one hour later. After screening 273 out of 602 women showed test serum glycose values > 125 mg/dL All 273 women received a l 00 gr 3-hour glycose tolerance test (GTT), Thirty out of 273 women were found to have carbohydrate into­lerance. The overall incidence of GDM was 4.98%, When the threshold glycose value was ::0: 130 mg/di the incidence of GDM was 17.8%, but lowering the threshold to 126 mg/dl a further 1.3% of the women showed carbohydrate intolerance. In the above thre­shold value the sensitivity was 100% but the specificity was only 54%. However, we recommend 126 mg/dl threshold for GIT since this threshold allows for the diagnosis of all women with carbohydrate intolerance during pregnancy.

Keywords
Glycose screening test
Gestational diabetes mellitus
Carbohydrate intolerance
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