IMR Press / CEOG / Volume 21 / Issue 3 / pii/1994036

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Original Research

lmmunohistochemical study of placental endothelium in physiologic and gestosis-complicated pregnancies

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1 Department of Obstetrics and Gynecology, University of Pisa, Italy
2 Institute of Pathologic Anatomy, University of Pisa, Italy
Clin. Exp. Obstet. Gynecol. 1994, 21(3), 192–194;
Published: 10 September 1994
Abstract

In this study we examined the placentae of gestosic patients and controls, with immunoistochemical method and HLA-DR monoclonal antibody, in order to show the role of placental endothelium in gestosic pathology onset. Our results show a marked expression of class II histocompatibility antigens in gestosic placentae with respect to controls. We suppose, in gestosic patients, a role for a particular, genetically determined HLA haplotype which increases disease receptivity.

Keywords
E.P.H. gestosis
Placental endothelium
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