The significance of the relationship between serum levels of cobalamin and MCHC during pregnancy

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Original Research

N. G. Carretti^1,*, A. G. Eremita¹, D. Paternoster², P. Pellizzari², B. Porcelli³, P. Grella²

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¹ Clinica Ostetrica e Ginecologica, dell’Universita di Siena, Italy

² Clinica Ostetrica e Ginecologica, dell’Universita di Padova, Italy

³ Istituto di Biochimica ed Enzimologia, dell’Universita di Siena, Italy

Clin. Exp. Obstet. Gynecol. 1993, 20(1), 20–22;

Published: 10 March 1993

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Abstract

Cobalamin concentration and mean corpuscular haemoglobin concentration (MCHC) were found to have highly significant inverse correlation with the weeks of pregnancy (respectively -.278 P < 0.0001 and .342 P < 0.00001) in 205 pregnant women. Among all haematometric parameters cobalamin concentrations during pregnancy only correlates with MCHC (P < .01). This datum seems to indicate an influence of B12 on erythropoiesis which adequate the concentration of haemoglobin to circulatory modifications of pregnant women.

Keywords

Cobalamin

Haematocrit

Pregnancy

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Clin. Exp. Obstet. Gynecol. Print ISSN 0390-6663 Electronic ISSN 2709-0094