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Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Original Research
Eicosanoid production in human umbilical cord vessels: effect of 17β-estradiol
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1
Department of Obstetrics and Gynecology, University of Tubingen
Clin. Exp. Obstet. Gynecol. 1992, 19(2), 112–116;
Published: 10 June 1992
Abstract
This study was designed to investigate the effects of 17β-estradiol on prostanoid formation from exogenous arachidonic acid in homogenates of human umbilical cord vessels. The veins produced more prostanoids than the arteries and predominantly 6-keto-PGF1 alpha. 17β-estradiol had no effect on the rate of production of prostanoids in either vessels. Thus, at least in our in vitro system, the regulation of the vascular tone by prostanoids seems not to be altered by the addition of 17β-estradiol.
Keywords
Human umbilical cord
17β-estradiol
Prostanoid metabolism