IMR Press / CEOG / Volume 19 / Issue 2 / pii/1634202754606-504218084

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 46 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Open Access Original Research

Eicosanoid production in human umbilical cord vessels: effect of 17β-estradiol

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1 Department of Obstetrics and Gynecology, University of Tubingen
Clin. Exp. Obstet. Gynecol. 1992, 19(2), 112–116;
Published: 10 June 1992
This study was designed to investigate the effects of 17β-estradiol on prostanoid formation from exogenous arachidonic acid in homogenates of human umbilical cord vessels. The veins produced more prostanoids than the arteries and predominantly 6-keto-PGF1 alpha. 17β-estradiol had no effect on the rate of production of prostanoids in either vessels. Thus, at least in our in vitro system, the regulation of the vascular tone by prostanoids seems not to be altered by the addition of 17β-estradiol.
Human umbilical cord
Prostanoid metabolism
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