IMR Press / CEOG / Volume 19 / Issue 1 / pii/1992001

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Original Research

Induction of labour with prostaglandin gel in patients with unfavourable cervices

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1 Consultant Obstetrician, North Tees General Hospital, Cleveland
2 Consultant Obstetrician, St Mary’s Hospital, Manchester
3 Consultant Obstetrician, Arrowe Park Hospital, Merseyside
4 Consultant Obstetrician, Gloucester Royal Hospital, Gloucester
5 Consultant Obstetrician, The Royal Infirmary, Glasgow
Clin. Exp. Obstet. Gynecol. 1992, 19(1), 5–8;
Published: 10 March 1992
Abstract

151 primigravid patients with Bishop scores of 4 or less were induced with prostaglandin E2 gel using an initial dose of 2 mg followed by 1 mg or 2 mg at 6 hours. Eighty one patients (53.6 per cent) were in established labour or had delivered by 12 hours, and a further 31 (20.5 per cent) had achieved successful ripening of the cervix. Ninety per cent and 64.5 per cent respectively achieved vaginal delivery and although 39 patients failed to respond to this regime, 72 per cent delivered vaginally after augmentation. No case of hypertonus was recorded and only one patient had abdominal delivery for “failed induction”. This regime provides an effective means of induction of labour for a difficult group of patients with little worry of overstimulation and low “failed induction” rates.

Keywords
Labour induction
Prostaglandin
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