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Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Original Research
The management of leiomyoma uteri by GnRH analogues
F. L. GIORGINO1,*, C. CETERA1
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1
Obstetric and Gynecologic Pathology Department University of Padua (Italy)
Clin. Exp. Obstet. Gynecol. 1991, 18(2), 137–143;
Published: 10 June 1991
Abstract
Therapy with GnRH analogs is the first medical solution to be really effective in treating uterine fibromas, even if with limited and temporary benefits. Out of the 12 patients treated the Authors observed that a 60% reduction of the volume of the uterus can be achieved after 3-6 months therapy, with rapid recuperation of the initial volume after interruption of the treatment. It is therefore preferable to use GnRH analogs as a propedeutic therapy rather than surgery.