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Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Case Report
The topical administration of steroids in the treatment of typical vulvar dystrophies
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1
Department of Obstetrics and Gynecology - University of Pisa (Italy)
Clin. Exp. Obstet. Gynecol. 1989, 16(1), 12–15;
Published: 10 March 1989
Abstract
Sixty-eight patients with histologically diagnosed typical vulvar dystrophies were treated with local administration of steroids. Twenty-three patients with hyperplastic dystrophies received topical fluorinated corticosteroids twice a day for 4 weeks and once a day for another 2 weeks. Thirty-five patients with lichen sclerosus were given local 2% testosterone propionate in vaseline twice a day for 8 weeks, once a day for another 8 weeks and then 3 times a week for another 8 weeks. Ten patients with mixed dystrophy first received topical fluorinated corticoste-roids twice a day for 4 weeks and once a day for another 2 weeks, and then local 2% testoste-rone propionate in vaseline twice a day for 4 weeks and once a day for another 4 weeks. A relief of symptomatol9gy and a regressjon of gross appearance were obtained in 82.6% and 69.6% of patients respectively with hyperplastic dystrophy, in 82.9% and 65.7% of those with lichen sclerosus and in 80% and 40% of those with mixed dystrophy. A recurrence of symptomatology often occurred at various times after the end of therapy.