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Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Original Research
Vulvar hormonal receptor modifications during topical steroid treatment
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1
Institute of Obstetrics and Gynaecology - University of Padua (Italy)
Clin. Exp. Obstet. Gynecol. 1988, 15(4), 170–173;
Published: 10 December 1988
Abstract
Four groups of 92 patients steroid pre-treated and non-treated vulvar tissues at delivery, during episiotomy, were used in determining androgen, estrogen and progesterone receptors. In 24 central specimens ER and AR concentrations turned out to be quite low when compared to the endometrium and the breast; PgR were much higher in both the cytoplasm and the nucleus, with a statistically significant difference. After estrogen, testosterone and progesterone topical treatment we observed interesting receptor status modifications which emphasize the use of vulvar receptors as marker during local therapy.