IMR Press / CEOG / Volume 15 / Issue 3 / pii/1634257369697-1646297354

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Original Research
Hsv2 and cervical intraepithelial neoplasia: cytological, histological and serological features
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1 Clinica Ostetrica e Ginecologica - Universita degli Studi, Cagliari (Italy)
Clin. Exp. Obstet. Gynecol. 1988, 15(3), 88–93;
Published: 10 September 1988
Abstract

An epidemiological investigation on the incidence of HSV2 infection in 1216 women with acute or recurrent vulvovaginitis was performed. HSV2 research was carried out by means of clinical, cytological, colposcopic, histologic examinations and vaginal pad cultures and antibody titration. Of the patients examined, 12.6% presented signs of genital herpes; among the diagnostic techniques used, the most reliable proved to be the serological method. Incidence of HSV2 was higher among women in the under privileged social classes, those who had sexual relations with different partners and those who were multiparous. A higher percentage of dysplastic and/or neoplastic lesions of the uterine cervix among HSV2 positive (P less than 0.025) with respect to controls was also found. A higher incidence of neoplastic pathologies among women who are positive for HSV2 was therefore confirmed.
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