IMR Press / CEOG / Volume 15 / Issue 1-2 / pii/1634257150231-194956143

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Original Research
Observations on the alkaline phosphatase isoenzyme distribution in maternal and amniotic fluid compartments in nigerian parturients
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1 Departtment of Obstetrics and Gynaecology - University of Benin (Nigeria)
2 Department of Chemical Pathology - University of Benin (Nigeria)
Clin. Exp. Obstet. Gynecol. 1988, 15(1-2), 13–17;
Published: 10 March 1988
Abstract

Estimation of the alkaline phosphates isoenzymes in paired maternal serum and amniotic fluids in term uncomplicated pregnancies and in patients with pre-eclampsia, showed poor correlation coefficients between the levels of both heat stable and heat labile isoenzymes. There was a statistically significant fall in AF (P less than .05) HSAP in pre-eclampsia and a highly significant rise of HLAP in meconial liquor. It is concluded that the poor correlation between the levels of HSAP in maternal serum and amniotic fluid (despite their common source of origin), the normal levels of HLAP in maternal serum in the presence of significantly high levels of HSAP in maternal serum in the presence of significantly diminished levels in amniotic fluid point to a state of relatively diminished permeability of the chorioamniotic membranes to the alkaline phosphatase isoenzymes in Nigerians.
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