IMR Press / CEOG / Volume 12 / Issue 3-4 / pii/1634257753960-530610699

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Original Research
Menstrual migraine, old and new
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1 Institute of Obstetrics and Gynaecological Clinic - University of Pavia (Italy)
2 Headaches Center Neurological Institute “C. Mondino” - University of Pavia (Italy)
Clin. Exp. Obstet. Gynecol. 1985, 12(3-4), 67–71;
Published: 10 September 1985

The authors reviewed the connection between sexual hormones and migraine crisis. Besides other exogenous factors, the fall of estradiol blood levels in the late luteal and premenstrual phase seems a causal factor in the origin of menstrual-related headache crisis. The behaviour of migraine crisis during the various events of female reproductive life, support this view. The role of PRL, T, FSH and LH was also discussed. On the other hand, menstrual migraine represents a model that fits perfectly with a neuroendocrine hypothesis which is based upon a faulty chronobiological response of the so-called antinociceptive system.
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