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Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Original Research
Hormonal changes and hair growth during treatment of hirsutism with cimetidine
R. Grandesso1, P. Spandri1, M. Gangemi2, G. B. Nardelli2, G. B. Ambrosio1, G. Conte1, D. De Salvia2, G. Meneghetti2
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1
Clinical Medicine Institute, Padua University (Italy)
2
Obstetric and Gynecologic Clinic, Padua University (Italy)
Clin. Exp. Obstet. Gynecol. 1984, 11(3), 105–109;
Published: 10 September 1984
Abstract
The effects on hair growth by treatment with cimetidine have been studied. This drug has been given orally to 4 women with simple hirsutism and 3 women with peptic ulcer as controls for a period of 9 months. Hair growth slowed down in all of the treated women but the results were not statistically significant. A significant decrease in urine 17-ketosteroids has been observed, while plasma levels of testosterone, 17-beta estradiol, progesterone, FSH, LH and prolactin, did not change substantially. It is concluded that, on the whole, cimetidine doses not seem to induce such results on hair growth as to claim a role in the treatment of hirsutism in other current regimes.