IMR Press / CEOG / Volume 11 / Issue 3 / pii/1634711514943-1833346061

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Original Research
Rapid diagnosis of herpesvirus hominis infection of cervix and vagina before delivery
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1 Institute of Microbiology and Immunology Clinic of Gynecology and Obstetrics School of Medicine, University of Belgrade (Yugoslavia)
Clin. Exp. Obstet. Gynecol. 1984, 11(3), 69–71;
Published: 10 September 1984
Abstract

The incidence of asymptomatic vaginal and cervical Herpes virus hominis shedding in a group of 51 pregnant women near term was investigated by the method of indirect immunofluorescence. All women were tested serologically by the method of microneutralisation in order to diagnose latent HVH type 1 or HVH type 2 infection. The shedding of HVH, in most cases, was the consequence of the activated HVH latent infection. It was revealed that 13.72% of asymptomatic HVH type 1 shedding was from vagina alone, and 7.27% of asymptomatic HVH type 1 shedding was from cervix alone. The same percentage (17%) of HVH type 2 shedding was revealed from both the vagina and the cervix. All women whose cervical and vaginal smears showed positive HVH type 1 or HVH type 2 immunofluorescence were latently infected. We have no direct data to refuse or confirm the suggestions that Caesarian section is recommended in women with genital herpes. The fact that both vaginal and cervical asymptomatic shedding of HVH occur during pregnancy indicates that these women undergo the virologic examination near term. The evaluation of duration of asymptomatic shedding is needed. Close clinical and virologic observation will markedly reduce both clinical and subclinical HVH infection of the newborn infant. In such circumstances rapid diagnosis of HVH infection becomes extremely important in the pregnant women.
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